Clinicians caring for patients receiving acute or maintenance dialysis frequently need to consider alternative medications within a therapeutic class. Choosing a drug that is less dialyzable can reduce the risk of removal during dialysis, ensuring more consistent therapeutic effects and minimizing the need for dosage adjustments post-dialysis. Other reasons for alternative medications may include lack of desired effect, intolerance, cost or formulary issues.
We are pleased to provide the following table, which compares antihypertensive agents. This is the first of a series of at-a-glance tables. We hope that these tables will be a useful supplement to our core product, Dialysis of Drugs.
Nancy A Mason and George R Bailie, July 2024